FROM:
Foundation for Chiropractic Education and Research (FCER)
October 24, 2002 Des Moines, Iowa— Patients afflicted with asthma may benefit from spinal manipulation in
terms of symptoms, immunological capacity, and endocrine effects, an
audience was told on October 5 at the 9th International Conference on
Spinal Manipulation in Toronto. The investigative team, headed by Ray
Hayek, Ph.D., has been conducting a trial at 16 treatment centers in
Australia involving 420 patients with an average age of 46 in an effort to
find out what effects spinal manipulation has on symptoms, depression and
anxiety, general health status, and the levels of immunity as reflected by
the concentrations of both an immunoglobulin (IgA) and an
immunosuppressant (cortisol). This investigation draws from several
references in the scientific literature which suggest that different forms
of manual therapy (including massage) improve the symptomatology and lower
cortisol levels in asthma patients.
Dr. Hayek reported that only the patient group which underwent spinal
manipulation (by any of four commonly used manipulative treatment
protocols) displayed significant improvement in asthma symptoms and
depression and anxiety scores. Simply experiencing structured interviews
at the treatment centers or being monitored at home did not yield these
improvements. In addition, patients actually undergoing spinal
manipulation displayed dramatic increases of IgA and decreases of cortisol
through the posttreatment period, suggesting that there were physiological
consequences to their manipulative treatments reflecting increased
immunological capacities which would be expected to ward off subsequent
asthmatic attacks.
These biochemical changes not only suggest that the effects of spinal
manipulation are more far-reaching than commonly believed, but that they
may be more long-term as well. The gain in immunological capacity achieved
with the simultaneous loss of the immunosuppressant cortisol and the
increase of the immunoglobulin IgA following spinal manipulation would be
expected to reduce the incidence and severity of pathogenic invasion of
the airways. There would be less of a risk under these circumstances of
compounding the symptoms of asthma.
The immunosuppressing mechanism of glucocorticoids is believed to occur by
their reducing the permeability of capillaries, decreasing the migration
of white blood cells in inflamed areas, suppressing the release of
interleukins, and inhibiting the production of proteolytic enzymes by
stabilizing the lysosomal membranes which release them.
This followed contacts that the Director of Research at FCER was able to
make with the Australian research community in 1995, taking into
consideration the expertise of the investigative team as well as the fact
that Australia's 2 million asthma sufferers have given the Island
Continent the dubious distinction of being the asthma capital of the
world. It has been carried out with the support of research grants
exceeding a quarter of a million dollars from both the Foundation for
Chiropractic Education and Research (FCER) and the National Chiropractic
Mutual Insurance Company (NCMIC). This research, which may be highly
influential on the future of the chiropractic profession, is still in need
of funding. To contribute to this important project, please call FCER at
800-637-6244, or donate via the Foundation's secure website at:
https://www.fcer.org:448/html/asthma_donate.asp
This research represents one of approximately 50 projects administered by
FCER since 1990 in the effort to document both the theory and practice of
chiropractic to increase its effective integration into healthcare systems
worldwide. The conference at which these results were presented is an
international forum which FCER has sponsored at different locations
worldwide for the past 14 years.