Table 2
Diagnostic accuracy in development dataset 1 using each level of the MAINTAIN instrument as possible discrimination thresholds to classify dysfunctional patients (96 individuals were classified as dysfunctional by the original instrument in this sample)
Development dataset 1 (n = 249) MS n (DYS) Sensitivity (%) Specificity (%) PPV (%) NPV (%) Youden’s index 8 229 100.0 13.0 41.5 100.0 0.110 9 224 100.0 16.2 42.4 100.0 0.130 10 220 100.0 18.8 43.2 100.0 0.162 11 218 100.0 20.1 43.6 100.0 0.188 12 205 100.0 28.6 46.3 100.0 0.201 13 201 100.0 31.2 47.3 100.0 0.286 14 193 100.0 36.4 49.2 100.0 0.312 15 180 98.9 44.2 52.2 98.6 0.364 16 173 98.9 48.7 54.3 98.7 0.431 17 159 96.8 56.5 57.9 96.7 0.476 18 146 95.8 64.3 62.3 96.1 0.533 19 140 94.7 67.5 64.3 95.4 0.601 20 133 90.5 69.5 64.7 92.2 0.623 21 122 86.3 74.0 67.2 89.8 0.600 22 109 81.1 79.2 70.6 87.1 0.603 23 103 75.8 79.9 69.9 84.2 0.603 24 92 70.5 83.8 72.8 82.2 0.557 25 84 63.2 84.4 71.4 78.8 0.543 26 74 60.0 89.0 77.0 78.3 0.476 27 67 55.8 90.9 79.1 76.9 0.490 MS, MAINTAIN Score (emphasis represent recommended thresholds);
n(DYS), number of individuals classified as dysfunctional by the MAINTAIN instrument at that threshold;
PPV, Positive Predictive Value;
NPV, Negative Predictive Value