Definition and classification for adverse events following spinal and peripheral joint manipulation and mobilization: A scoping review

Martha Funabashi; Lindsay M. Gorrell; Katherine A. Pohlman; Andrea Bergna; Nicola R. Heneghan

doi:10.1371/journal.pone.0270671

Table 6

Studies providing indirect adverse event definition only (n = 4).

Authors, year, citation Study design Definition
Giles et al. 2003 [98] Observational Study Events requiring remedial treatment; minor transient increase in spinal pain symptoms that did not qualify as an adverse event
Hay et al. 2005 [94] Trial “An exacerbation of pain after the initial assessment’’
de Oliveira et al. 2013 [32] Trial “Did your symptoms get worse after this treatment?”
“Are you feeling any different symptom after this treatment?”
Satpute et al. 2020 [99] Case Reports/Series “There were no adverse events during or after each treatment session in terms of dizziness, increase in pain intensity, or induction of other symptoms.’’

Authors, year, citation	Study design	Definition
Giles et al. 2003 [98]	Observational Study	Events requiring remedial treatment; minor transient increase in spinal pain symptoms that did not qualify as an adverse event
Hay et al. 2005 [94]	Trial	“An exacerbation of pain after the initial assessment’’
de Oliveira et al. 2013 [32]	Trial	“Did your symptoms get worse after this treatment?”
de Oliveira et al. 2013 [32]	Trial	“Are you feeling any different symptom after this treatment?”
Satpute et al. 2020 [99]	Case Reports/Series	“There were no adverse events during or after each treatment session in terms of dizziness, increase in pain intensity, or induction of other symptoms.’’