Dietary Fiber Intake and Type 2 Diabetes Mellitus: An Umbrella Review of Meta-analyses

doi:10.1016/j.jcm.2017.11.002

Table 5

Effects of Increased Fiber Intake on Changes in HbA1c%

Meta-analysis Authors and Date	No. of Studies in Meta-analysis	No. of Participants in Meta-analysis	Fiber Type and Dose/Day	Mean Duration in Weeks	Reduction in HbA1c%	Q Test P Value and I² Statistic	Egger or Begg Test P Value	Quality Assessment and Outcome
Post et al, 2012²³^a	10 T2D	324	Soluble 16 g	8	↓ 0.26, P < .05	NS, 21%		GRADE 9/10 high quality

Silva et al, 2013²⁴	11 T2D	605	Soluble 15 g	11	↓ 0.52, P < .05	P < .001, 94%	NS	GRADE NR

Hou et al, 2015²⁹	6 T2D	437	β-Glucan NR	4.5	↓ 0.42, P < .001	NS, 18%		NOS 5/6 high quality

Shen et al, 2016³⁰	4 T2D	139	β-Glucan 3 g	4.5	↓ 0.21, P < .05	NS, 0%	NS	Cochrane 3/4 high quality

He et al, 2016³¹	4 T2D	229	β-Glucan 3.5 g	5.5	↓ 0.22, NS	P < .001, 92%

HbA1c%, glycosylated hemoglobin percentage;
NOS, Newcastle-Ottawa Scale;
NR, not reported;
NS, not significant;
T2D, participants with type 2 diabetes only.

^aLow-quality score on the Critical Appraisal Checklist for Systematic Review.