Nutrient biomarker patterns, cognitive function, and MRI measures of brain aging

doi:10.1212/WNL.0b013e3182436598

Table 3

Nutrient biomarker patterns associated with cognitive function (n = 104)

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Abbreviations: NBP = nutrient biomarker pattern; NBP1 = BCDE; NBP2 = saturated fat; NBP3 = carotenoid; NBP4 = cholesterol; NBP5 = marine ω-3; NBP6 = ω-6 + retinol; NBP7 = lutein + high-density lipoprotein cholesterol; NBP8 = trans fat.

^aGlobal z score includes the sum of the domain z scores divided by 6. Reverse coding for executive and processing speed created a uniform direction for the coefficient (positive coefficient = superior performance).

^bModel 1: cognitive measure = 8 NBPs + age + gender + education + APOE4.

^cModel 2: cognitive measure = model 1 + hypertension + depression.

^dp < 0.01.

^ep < 0.05.