Figure 7

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Effect of glyceollins on cognitive function in Nrf2 knockout mice. Nrf2 knockout C57BL/6 mice (five weeks old, n = 7) were pretreated with glyceollins (10 mg/kg bw) 24 h before cognitive function or behavior tests, and then subjected to Y-maze (A); passive avoidance (B); and Morris Water maze (C) tests after injected i.p. with scopolamine (1 mg/kg bw). Different alphabetical letters (a, b) on bars indicate statistically significant differences.