Neural Correlates of Fear of Movement in Patients with Chronic Low Back Pain vs. Pain-Free Individuals

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Published online 2016 Jul 26. doi: 10.3389/fnhum.2016.00386

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Table 2

Cluster maxima and their respective coordinates.

Cluster size	p(FWE)	F	MNI coordinates (mm)			Brain region (AAL label)
			x	y	z
a. Factorial analysis (ANOVA), average effect of condition, contrast “harmful activites > neutral activities”
9137	0.001	218.63	−54	−68	2	Left middle temporal gyrus (Temporal_Mid_L)
2317	0.001	142.25	48	−64	2	Right middle temporal gyrus (Temporal_Mid_R)
927	0.001	115.56	24	−54	62	Right superior parietal cortex (Parietal_Sup_R)
306	0.001	78.09	−20	0	66	Left superior frontal gyrus (Frontal_Sup_L)
79	0.001	77.88	52	22	10	Right inferior frontal gyrus (Frontal_Inf_Tri_R)
8	0.004	50.48	−26	0	−26	Left amygdala (Amygdala_L)
b. Voxel-wise regression analysis, positive correlations with TSK score, contrast “harmful activites > neutral activities”
349	0.001	6.04	−24	20	−22	Left orbitofrontal cortex (Fontral_inf_Orb_L)
194	0.001	5.82	−52	−32	−14	Left middle temporal gyrus (Temporal_Mid_L)
314	0.001	5.81	−4	−38	58	Left postcentral gyrus (Precuneus_L)
79	0.043	4.78	−58	−6	12	Left rolandic operculum (Rolandic_Oper_L)
339	0.001	4.64	−40	−56	34	Left angular gyrus (Angular_L)

FWE, family-wise error;
MNI, Montreal Neurological Institute;
AAL, Automated Anatomical Labeling.