| Author, Year, Followup,a Pain Duration, Study Quality | Intervention | Population | Function and Pain Outcomes | Other Outcomes |
|---|---|---|---|---|
Alfano, 2001167 6 months Duration of pain: >3 months (mean NR) Fair | A. Magnetic mattress pad designed to expose body to a uniform magnetic field of negative polarity (n=37) B. Magnetic mattress pad exposing body to magnetic field that varied spatially and in polarity (n=33) C. Sham magnetic field (n=32): combined group of 2 sham magnetic mattress pads; identical in appearance to real magnetic pads but contained demagnetized magnets. D. Usual care (n=17): maintain current treatment under PCP, refrain from new treatments Treatment period was 6 months for all groups. | A vs. B vs. C vs. D Age: 44 vs. 47 vs. 46 vs. 45 years Female: 92% vs. 87% vs. 96% vs. 100% Baseline FIQ (0-80): 51.6 vs. 55.5 vs. 51.5 vs. 53.9 Baseline pain intensity FIQ NRS (0-10): 7.1 vs. 7.0 vs. 6.7 vs. 7.0 | A + B vs. C Post 6-month intervention FIQ: 42.9 vs. 47.9, difference −5.0 (95% CI −14.1 to 4.1) Pain intensity NRS: 5.6 vs. 6.2, difference −0.6 (95% CI −1.9 to 0.7) A + B vs. D Post 6-month intervention FIQ: 42.9 vs. 48.4, difference −5.5 (95% CI −14.4 to 3.4) Pain intensity NRS: 5.6 vs. 6.6, difference −1.0 (95% CI −2.2 to 0.2) A vs. C Post 6-month intervention FIQ: 38.3 vs. 47.9, difference −9.6 (95% CI −20.0 to 0.8) Pain intensity NRS: 4.8 vs. 6.2, difference −1.4 (95% CI −2.8 to 0.05) B vs. C Post 6-month intervention FIQ: 47.4 vs. 47.9, difference −0.5 (95% CI −11.2 to 10.2) Pain intensity NRS: 6.3 vs. 6.2, difference 0.1 (95% CI −1.4 to 1.6) A vs. D Post 6-month intervention FIQ: 38.3 vs. 48.4, difference −10.1 (95% CI −21.9 to 1.7) Pain intensity NRS: 4.8 vs. 6.6, difference −1.8 (95% CI −3.4 to −0.2) B vs. D Post 6-month intervention FIQ: 47.4 vs. 48.4, difference −1.0 (95% CI −13.0 to 11.0), Pain intensity NRS: 6.3 vs. 6.6, difference −0.3 (95% CI −2.0 to 1.4) | NR |
Paolucci, 2016168 1 month Duration of pain: Poor | A. Extremely low-frequency magnetic field first (n=16): three 30-minute sessions per week for 4 weeks (12 sessions total). Patients laid on a bed with multi-low-frequency mattress that delivered a magnetic field at an intensity of 100 uT and a multifrequency of 1 to 80 Hz. B. Sham extremely low-frequency magnetic field first (n=17): three 30-minute sessions per week for 4 weeks (12 sessions total). Patients laid on a bed with multi-low-frequency mattress but no magnetic field was delivered. Washout period: 1 month | A vs. B Age, years: 50 vs. 51 Female: 100% vs. 100% Fibromyalgia duration, years: 7 vs. 5 Baseline FIQ: 58.7 (11.3) vs. 57.2 (12.3) Baseline pain VAS: 4.9 (1.4) vs. 4.8 (1.2) Baseline FAS (0−10): 6.1 (1.7) vs. 6.4 (1.4) | A vs. B, mean 1 month FIQ: 19.2 vs. 57.9, p<0.001 Percent change from baseline in FIQ: −67.3% vs. 2.9%, p<0.001 Pain VAS: 2.2 vs. 5.3, p<0.001 Percent change from baseline in pain VAS: −54.1% vs. 6.3%, p<0.001 FAS: 3.2 vs. 6.1, p<0.001 Percent change from baseline in FAS: −46.5% vs. −4.5% p<0.001 B vs. A (after cross-over) 1 month FIQ: 25.1 vs. 53.9, p<0.001 Percent change from baseline in FIQ: −56.0% vs. −8.1%, p<0.001 Pain VAS: 3.1 vs. 4.6, p=0.02 Percent change from baseline in pain VAS: −39.7% vs. −9.1%, p=0.006 FAS: 3.5 vs. 6.2, p=0.002 Percent change from baseline in FAS: −46.9% vs. −1.2%, p<0.001 | A vs. B 1 month HAQ (0-3): 0.3 vs. 1.1, p=0.03 Percent change from baseline in HAQ: NR B vs. A (after cross-over) 1 month HAQ: 0.7 vs. 0.8, p=0.41 |
Unless otherwise noted, followup time is calculated from the end of the treatment period
From: Results
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