From the February 2001 Issue of Nutrition Science News

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Drug	Nutrient Depletions	Potential Depletion Problems
Barbituates (Amytal, Tuinal, Butalan, Buticaps, Butisol Sodium, Mebaral, Brevital, Barbita, Nembutal, Luminal, Solfoton, Seconal, Pentothal)	Calcium	Heart/blood pressure irregularities, osteoporosis, tooth decay
	Folic acid	Anemia, birth defects, cardiovascular disease, cervical dysplasia
	Vitamin D	Hearing loss, muscle weakness, osteoporosis
	Vitamin K	Blood clotting and skeletal problems
Phenytoin (Dilantin)	Biotin	Cardiac irregularities, depression, dermatitis, hair loss
	Calcium	Heart/blood pressure irregularities, osteoporosis, tooth decay
	Folic acid	Anemia, birth defects, cardiovascular disease, cervical dysplasia
	Vitamin B1	Depression, edema, irritability, memory loss, muscle weakness
	Vitamin B12	Anemia, increased cardiovascular risk, tiredness, weakness
	Vitamin D	Blood coagulation and skeletal problems
Carbamazepine (Carbatrol, Epitol, Tegretol)	Biotin	Cardiac irregularities, depression, dermatitis, hair loss
	Folic acid	Hearing loss, musle weakness, osteoporosis
	Vitamin D	Anemia, birth defects, cardiovascular disease risk, cervical dysplasia
Primidone (Mysoline)	Biotin	Anemia, birth defects, cardiovascular disease risk, cervical dysplasia
	Folic acid	Cardiac irregularities, depression, dermatitis, hair loss
Valproic Acid (Depacon, Depakene, Depakote)	Carnitine	Cramps, fatigue, muscle weakness
	Folic acid	Anemia, birth defects, cardiovascular disease risk, cervical dysplasia
The scientific basis for this information is from published studies using these drugs or drugs from the same pharmacological class. Advise customers to ask their doctor or pharmacist if any of their medications can cause nutrient depletions.
Reprinted with permission from Drug-Induced Nutrient Depletion Handbook (Lexi-Comp, 1999) by Ross Pelton, Ph.D., C.N.; James B. LaValle, N.D., C.N., D.H.M.; Ernest B. Hawkins; and Daniel L. Krinsky.

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Since 2-01-2001