Blueberry Extract
(Vitis vinifera)

This section was compiled by Frank M. Painter, D.C.
Send all comments or additions to:   Frankp@chiro.org

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Blueberry Extract Articles

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	Inhibitory Effects of Wild Blueberry Anthocyanins and Other Flavonoids on Biomarkers of Acute and Chronic Inflammation in Vitro J Agric Food Chem. 2014 (Jul 23);   62 (29):   7022–7028 Among major polyphenols found in the wild blueberries, malvidin-3-glucoside was significantly more effective than epicatechin or chlorogenic acid in reducing the expression of pro-inflammatory genes in vitro.
	Effect of a Polyphenol-rich Wild Blueberry Extract on Cognitive Performance of Mice, Brain Antioxidant Markers and Acetylcholinesterase Activity Behav Brain Res. 2009 (Mar 17);   198 (2):   352–358 Blueberry is very high in polyphenol content, so it can provide powerful antioxidant protection. A fortunate group of mice were fed an extract from blueberry for 7 days by these Greek physiologists. During testing, this blueberry-enhanced group of mice exhibited significant improvements in their memory and their ability to learn new tasks. The authors concluded that: “These findings stress the critical impact of wild blueberry bio-active components on brain function.”
	The Beneficial Effects of Fruit Polyphenols on Brain Aging Neurobiol Aging. 2005 (Dec);   26 Suppl 1:   128–132 Research from our laboratory has shown that nutritional antioxidants, such as the polyphenols found in blueberries, can reverse age-related declines in neuronal signal transduction as well as cognitive and motor deficits. Furthermore, we have shown that short-term blueberry (BB) supplementation increases hippocampal plasticity. These findings are briefly reviewed in this paper.

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